Thioridazine

Thioridazine
Thioridazine
Thioridazine
Général
Nom IUPAC 10-{2-[(RS)-1-méthylpipéridin-2-yl]éthyl}-2-méthylsulfanyl-phénothiazine
No CAS 50-52-2
No EINECS 200-044-2
Code ATC N05AC02
DrugBank APRD00596
PubChem 5452
SMILES
InChI
Propriétés chimiques
Formule brute C21H26N2S2  [Isomères]
Masse molaire[1] 370,575 ± 0,029 g·mol-1
C 68,06 %, H 7,07 %, N 7,56 %, S 17,31 %,
Propriétés physiques
T° fusion 73 °C
Pression de vapeur saturante 1,42×10-9 mmHg à 25 °C
Écotoxicologie
DL50 (souris, oral, 385 mg·kg-1)
Données pharmacocinétiques
Liaison protéique 95%
Métabolisme hépatique
Demi-vie d’élim. 7–13 heures (jusqu'à 20 heures)
Excrétion fèces
Considérations thérapeutiques
Voie d’administration orale
Unités du SI & CNTP, sauf indication contraire.

La thioridazine (Melleril) est un antipsychotique typique.

Notes et références

  1. Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.

Wikimedia Foundation. 2010.

Contenu soumis à la licence CC-BY-SA. Source : Article Thioridazine de Wikipédia en français (auteurs)

Игры ⚽ Нужен реферат?

Regardez d'autres dictionnaires:

  • Thioridazine — Not to be confused with Thorazine. Thioridazine Systematic (IUPAC) name …   Wikipedia

  • thioridazine hydrochloride — An antipsychotic with action similar to that of chlorpromazine but with relatively stronger anticholinergic effects. * * * [USP] the monohydrochloride salt of thioridazine, having the same actions and uses as the base; administered orally …   Medical dictionary

  • thioridazine — noun Etymology: thi + piperidine + phenothiazine Date: 1959 a phenothiazine tranquilizer C21H26N2S2 used in the form of its hydrochloride for relief of anxiety states and in the treatment of psychotic disorders and severe childhood behavioral… …   New Collegiate Dictionary

  • thioridazine — /thuy euh rid euh zeen , zin/, n. Pharm. a phenothiazine, C21H26N2S2, used as an antipsychotic chiefly in the treatment of acute psychoses and schizophrenia. [1955 60; THIO + (PIPE)RID(INE) + AZINE] * * * …   Universalium

  • thioridazine — noun An antipsychotic drug used in the treatment of anxiety, depression and autism …   Wiktionary

  • thioridazine — thio·rid·a·zine .thī ə rid ə .zēn, zən n a phenothiazine tranquilizer used in the form of its hydrochloride C21H26N2S2·HCl for relief of anxiety states and in the treatment of psychotic disorders and severe childhood behavioral problems see… …   Medical dictionary

  • thioridazine — thi·o·rid·a·zine …   English syllables

  • thioridazine — noun a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disorders • Syn: ↑Mellaril • Usage Domain: ↑trade name (for: ↑Mellaril) • Hypernyms: ↑ …   Useful english dictionary

  • 50-52-2 — Thioridazine Thioridazine Général Nom IUPAC 10 {2 [(RS) 1 Methylpiperidin 2 yl]ethyl} 2 methylsulfanyl phenothiazine …   Wikipédia en Français

  • C21H26N2S2 — Thioridazine Thioridazine Général Nom IUPAC 10 {2 [(RS) 1 Methylpiperidin 2 yl]ethyl} 2 methylsulfanyl phenothiazine …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”