Thioridazine


Thioridazine
Thioridazine
Thioridazine
Général
Nom IUPAC 10-{2-[(RS)-1-méthylpipéridin-2-yl]éthyl}-2-méthylsulfanyl-phénothiazine
No CAS 50-52-2
No EINECS 200-044-2
Code ATC N05AC02
DrugBank APRD00596
PubChem 5452
SMILES
InChI
Propriétés chimiques
Formule brute C21H26N2S2  [Isomères]
Masse molaire[1] 370,575 ± 0,029 g·mol-1
C 68,06 %, H 7,07 %, N 7,56 %, S 17,31 %,
Propriétés physiques
T° fusion 73 °C
Pression de vapeur saturante 1,42×10-9 mmHg à 25 °C
Écotoxicologie
DL50 (souris, oral, 385 mg·kg-1)
Données pharmacocinétiques
Liaison protéique 95%
Métabolisme hépatique
Demi-vie d’élim. 7–13 heures (jusqu'à 20 heures)
Excrétion fèces
Considérations thérapeutiques
Voie d’administration orale
Unités du SI & CNTP, sauf indication contraire.

La thioridazine (Melleril) est un antipsychotique typique.

Notes et références

  1. Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.

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Contenu soumis à la licence CC-BY-SA. Source : Article Thioridazine de Wikipédia en français (auteurs)

Regardez d'autres dictionnaires:

  • Thioridazine — Not to be confused with Thorazine. Thioridazine Systematic (IUPAC) name …   Wikipedia

  • thioridazine — noun Etymology: thi + piperidine + phenothiazine Date: 1959 a phenothiazine tranquilizer C21H26N2S2 used in the form of its hydrochloride for relief of anxiety states and in the treatment of psychotic disorders and severe childhood behavioral… …   New Collegiate Dictionary

  • thioridazine — /thuy euh rid euh zeen , zin/, n. Pharm. a phenothiazine, C21H26N2S2, used as an antipsychotic chiefly in the treatment of acute psychoses and schizophrenia. [1955 60; THIO + (PIPE)RID(INE) + AZINE] * * * …   Universalium

  • thioridazine — noun An antipsychotic drug used in the treatment of anxiety, depression and autism …   Wiktionary

  • thioridazine — thio·rid·a·zine .thī ə rid ə .zēn, zən n a phenothiazine tranquilizer used in the form of its hydrochloride C21H26N2S2·HCl for relief of anxiety states and in the treatment of psychotic disorders and severe childhood behavioral problems see… …   Medical dictionary

  • thioridazine — thi·o·rid·a·zine …   English syllables

  • thioridazine — noun a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disorders • Syn: ↑Mellaril • Usage Domain: ↑trade name (for: ↑Mellaril) • Hypernyms: ↑ …   Useful english dictionary

  • thioridazine hydrochloride — An antipsychotic with action similar to that of chlorpromazine but with relatively stronger anticholinergic effects. * * * [USP] the monohydrochloride salt of thioridazine, having the same actions and uses as the base; administered orally …   Medical dictionary

  • 50-52-2 — Thioridazine Thioridazine Général Nom IUPAC 10 {2 [(RS) 1 Methylpiperidin 2 yl]ethyl} 2 methylsulfanyl phenothiazine …   Wikipédia en Français

  • C21H26N2S2 — Thioridazine Thioridazine Général Nom IUPAC 10 {2 [(RS) 1 Methylpiperidin 2 yl]ethyl} 2 methylsulfanyl phenothiazine …   Wikipédia en Français


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