Fluphenazine


Fluphenazine

Fluphénazine

Fluphénazine
Fluphénazine
Général
Nom IUPAC 2-[4-[3-[2-(trifluoromethyl)-
10H-phenothiazin-10-yl]propyl]-
piperazin-1-yl]ethanol
No CAS 69-23-8
No EINECS 200-702-9
Code ATC N05AB02
DrugBank APRD00633
PubChem 3372
Propriétés chimiques
Formule brute C22H26F3N3OS
Masse molaire 437,522 gmol-1
C 60,39 %, H 5,99 %, F 13,03 %, N 9,6 %, O 3,66 %, S 7,33 %,
Propriétés physiques
T° fusion <25 °C[1]
Pression de vapeur saturante 1.02E-12 mmHg à 25 °C[1]
Écotoxicologie
DL50 (souris, oral, 220 mg/kg)[1]
Données pharmacocinétiques
Biodisponibilité 40 à 50%
Métabolisme hépatique
Demi-vie d’élim. 15 à 30 heures
Excrétion bile et fèces
Considérations thérapeutiques
Voie d’administration orale[2], intramusculaire[2]
Unités du SI & CNTP, sauf indication contraire.

La fluphénazine (Modecate, Moditen) est un antipsychotique typique.

Notes et références

  1. a , b  et c (en) « Fluphénazine » sur ChemIDplus, consulté le 4 août 2009
  2. a  et b (en) « Fluphénazine » sur DrugBank, consulté le 4 août 2009
  • Portail de la chimie Portail de la chimie
  • Portail de la médecine Portail de la médecine
  • Portail de la pharmacie Portail de la pharmacie
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Contenu soumis à la licence CC-BY-SA. Source : Article Fluphenazine de Wikipédia en français (auteurs)

Regardez d'autres dictionnaires:

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  • Fluphénazine — Général Nom IUPAC 2 [4 [3 [2 (trifluoromethyl) 10H phenothiazin 10 yl]propyl] piperazin 1 yl]ethanol …   Wikipédia en Français

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  • fluphenazine — noun Etymology: fluor + phenazine Date: 1959 a tranquilizer C22H26F3N3OS used especially in the form of its hydrochloride …   New Collegiate Dictionary

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  • fluphenazine hydrochloride — A drug that is used to treat mental and emotional disorders and is being studied in the treatment of multiple myeloma. Fluphenazine hydrochloride may stop tumor growth by keeping myeloma cells from dividing and causing them to die. It is a type… …   English dictionary of cancer terms


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