Pentazocine

Pentazocine
Pentazocine
Pentazocine
Général
Nom IUPAC (1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-en-1-yl)-
10-azatricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol
No CAS 359-83-1
No EINECS 206-634-6
Code ATC N02AD01
DrugBank APRD01173
PubChem 441278
SMILES
InChI
Propriétés chimiques
Formule brute C19H27NO  [Isomères]
Masse molaire[1] 285,4238 ± 0,0176 g·mol-1
C 79,95 %, H 9,53 %, N 4,91 %, O 5,61 %,
Propriétés physiques
T° fusion 146,3 °C
Précautions
Inhalation orale
Données pharmacocinétiques
Biodisponibilité ~20 % oralement
Métabolisme hépatique
Demi-vie de distrib. 2 à 3 heures
Excrétion rénale
Unités du SI & CNTP, sauf indication contraire.

La pentazocine est un opioïde.

Notes et références

  1. Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.

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  • pentazocine — ● pentazocine nom féminin Dérivé hémisynthétique de la morphine …   Encyclopédie Universelle

  • pentazocine — ☆ pentazocine [pen΄tə zō′sēn΄, pen΄tə zō′sin ] n. [ PENTA + (A)Z(O) + ocine, suffix for an 8 membered ring < L oc(to), EIGHT + INE3] a pain killing, synthetic drug derived from coal tar: used in place of morphine because it is less addictive …   English World dictionary

  • Pentazocine — Drugbox IUPAC name = (1 S ,9 S ,13 S ) 1,13 dimethyl 10 (3 methylbut 2 en 1 yl) 10 azatricyclo [7.3.1.02,7] trideca 2,4,6 trien 4 ol width = 180 CAS number = 359 83 1 ATC prefix = N02 ATC suffix = AD01 PubChem = 441278 DrugBank = APRD01173 C = 19 …   Wikipedia

  • pentazocine hydrochloride — [USP] the hydrochloride salt of pentazocine, administered orally as an analgesic …   Medical dictionary

  • pentazocine lactate — [USP] the lactate salt of pentazocine, administered intramuscularly, intravenously, or subcutaneously as an analgesic and as an adjunct to anesthesia …   Medical dictionary

  • pentazocine — noun Etymology: probably from penta + az + octa + 2 ine Date: 1963 a synthetic analgesic drug C19H27NO that is less addictive than morphine …   New Collegiate Dictionary

  • pentazocine — /pen taz euh seen /, n. Pharm. a synthetic narcotic analgesic, C19H27NO, used chiefly for the relief of moderate to severe pain. [1960 65; PENTA + (benz)azocine, a component of its chemical name] * * * …   Universalium

  • pentazocine — noun A particular narcotic painkiller of the benzomorphan class of opioids …   Wiktionary

  • pentazocine — An opioid agonist/antagonist analgesic with some addiction liability but only rare withdrawal syndrome and tolerance; very irritating to tissues on local injection; available as the hydrochloride and lactate salts. * * * pen·taz·o·cine pen taz ə …   Medical dictionary

  • pentazocine — pen·taz·o·cine …   English syllables

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